Successful prevention of BK-polyomavirus nephropathy using extracorporeal photopheresis for immunosuppression minimisation following severe BK polyomavirus replication after kidney transplantation in a double lung transplant recipient, a case report

Successful prevention of BK-polyomavirus nephropathy using extracorporeal photopheresis for immunosuppression minimisation following severe BK polyomavirus replication after kidney transplantation in a double lung transplant recipient, a case report

Blog Article

Abstract Background BK-polyomavirus (BKpyV) nephropathy (BKVN) is associated with end-stage kidney disease in SUPER LIP CARE + kidney and non-kidney solid organ transplantation, with no curative treatment.Case presentation A 45-year-old woman with a past medical history of double lung transplantation subsequently developed end-stage kidney disease, of undetermined origin.One month after receiving a kidney transplant, a diagnosis of early BKVN was suspected, and in retrospect was a reasonable cause for the loss of her native kidneys.Minimisation of immunosuppression, achieved through extracorporeal photopheresis, allowed clearance Tape Measurers of BKpyV and so prevented nephropathy.

Both lung and kidney grafts had a satisfactory and stable function after one year of follow-up, with no rejection.Conclusions Extracorporeal photopheresis may have facilitated minimisation of immunosuppression and BKpyV clearance without lung allograft rejection.